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Association of E484K Spike Protein Mutation With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Vaccinated Persons: Maryland, January-May 2021

Clinical Infectious Diseases (2022) 74(11) 2053-2056
DOI: 10.1093/cid/ciab762
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Abstract

Among 9048 people infected with SARS-CoV-2 between January and May 2021 in Maryland, in regression-adjusted analysis, SARS-CoV-2 viruses carrying the spike protein mutation E484K were disproportionately prevalent among persons infected after full vaccination against COVID-19 compared with infected persons who were not fully vaccinated (aOR, 1.96; 95% CI: 1.36-2.83).

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Feder, K. A., Patel, A., Vepachedu, V. R., Dominguez, C., Keller, E. N., Klein, L., … Myers, R. (2022). Association of E484K Spike Protein Mutation With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Vaccinated Persons: Maryland, January-May 2021. Clinical Infectious Diseases, 74(11), 2053–2056. https://doi.org/10.1093/cid/ciab762

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