We investigated the clinical features and treatment results of 24 cats with mast cell tumors (MCTs), including cutane-ous (c-MCT, n=17), splenic (s-MCT, n=2), and simultaneous cutaneous and splenic types (cs-MCT, n=5). Cutaneous lesions were treated by surgical excision or glucocorticoid therapy, and six of seven splenic lesions were treated by splenectomy. Of the 22 cats with c-or cs-MCT, six cats (four with c-MCT, and two with cs-MCT) had one to three distant recurrences (at a skin site distant from the original site) after initial treatment. Of the 31 c-MCTs in these 22 cats, eight were treated with glucocorticoid therapy, which led to complete remission of seven c-MCTs (88%); the other 23 c-MCTs were surgically excised, with only one (4%) recurrence at the surgical site. Although eight of 24 cats (33%) developed recurrent lesions, tumor-related death only occurred in one cat with cs-MCT (4%) during the follow-up period (range 30 to 2,364 days, median 537 days). These results suggest that both surgery and glucocorticoid therapy were effective in local control of c-MCTs, and that long-term survival can be expected, even in cats with s-MCTs who have undergone splenectomy. MCT 24 17 2 5 GC 6/7 22 6 4 2 1 3 31 GC 7/8 88% 23 1 4% 24 33% 30 2,364 537 1 4% MCT GC MCT Jpn.
CITATION STYLE
KOJIMOTO, A., ITOH, T., UCHIDA, K., CHAMBERS, J., & SHII, H. (2017). Clinicopathological Features and Treatment Results of 24 Cats with Mast Cell Tumors. Japanese Journal of Veterinary Anesthesia & Surgery, 48(1+2), 1–8. https://doi.org/10.2327/jjvas.48.1
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