Ammonium tetrathiomolybdate as a water-soluble and slow-release hydrogen sulfide donor

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Abstract

Ammonium tetrathiomolybdate (TTM) was found to be a slow hydrogen sulfide (H2S) releasing agent. Its H2S generation capability in aqueous solutions was confirmed by UV–vis and fluorescence assays. TTM also showed H2S-like cytoprotective effects in hydrogen peroxide (H2O2)-induced oxidative damage in HaCaT cells.

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Xu, S., Yang, C. T., Meng, F. H., Pacheco, A., Chen, L., & Xian, M. (2016). Ammonium tetrathiomolybdate as a water-soluble and slow-release hydrogen sulfide donor. Bioorganic and Medicinal Chemistry Letters, 26(6), 1585–1588. https://doi.org/10.1016/j.bmcl.2016.02.005

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