Verification of the analytical performance of the serum glucose assay on the Abbott Alinity ci®

Abstract

The precision and reliability of the serum glucose assay on the Abbott Alinity ci® analyzer were systematically evaluated. The study was conducted over 30 days in the biochemistry laboratory of Mohammed VI University Hospital. Two phases were carried out: reproducibility assessment involving daily measurements across low, medium, and high glucose levels, and repeatability testing involving 30 replicates per sample. The hexokinase enzymatic approach was employed for glucose quantification. Data analysis utilized the BYG middleware and complied with FSCB and RICOS standards. For reproducibility, the coefficient of variation (CV) values were low, ranging from 1.49% to 1.84%. Repeatability CV values were even lower, varying from 0.34% to 0.94%. Results aligned well with quality control limits, confirming the assay's consistency and precision. This study underscores the robustness and reliability of the hexokinase method on the Alinity ci® platform for serum glucose analysis, with implications for accurate patient care. By adhering to strict analytical performance verification, laboratories ensure dependable clinical outcomes. This research contributes to the foundation of knowledge supporting serum glucose measurement reliability.