Synthesis of aminothiazoles: Polymer-supported approaches

Abstract

Aminothiazoles and their derivatives are of immense biological importance and have been consistently synthesized via various methods. However, the synthesis of aminothiazole derivatives has some problems such as poor yields, difficult isolation procedures, use of expensive catalysts etc. Recently, polymer or solid-supported synthetic protocols have attracted the attention from the research community because of their easy execution, increased product yields, greater selectivity, simple work-up procedures, and recoverability of the catalysts. In this study, we reported the polymer-supported approaches for the synthesis of differently substituted aminothiazoles.