Comparación entre cuestionario de control de asma en niños (CAN) y recomendaciones de control GINA

Abstract

Introduction: Several questionnaires of asthma control exist for children, but few of them have been validated in Spanish being applicable to our country. Patients and Methods: We compared the asthma control questionnaire in children (CAN) in two versions in Spanish with the control questionnaire recommended by GINA. The study was carried out at Roberto del Río Children's Hospital, Santiago de Chile. We measured concordance and diagnostic tests. The sample size was calculated considering a power of 80% and a p value < 0,05. Results: We enrolled to 214 asthmatic children from 5 to 14 years-old. Male gender 60.3%. Mean of age was 8.3 years. Controlled asthma in children 5 to 8 years-old was 12.1% for GINA and 35.6% for CAN guardian version. CAN guardian achieved 76.5% to agree in uncontrolled asthma (Kappa 0.39). Sensitivity, specificity, positive predictive and negative predictive values for children from 5 to 8 years-old were 100%, 73%, 34% and 100% respectively. Controlled asthma in children from 9 to 14 years-old reached 23.2% with GINA and 43.9% with CAN. The 79.2% of the controlled asthmatic by GINA were correctly diagnosed by CAN (Kappa 0.55). Sensitivity, specificity, positive predictive and negative predictive values in 9 to 14 years-old children were 100%, 73%, 53% and 100% respectively. Conclusion: CAN is an instrument of easy implementation in our practice that achieves acceptable agreement with GINA recommendations, whose main utility is in identifying the patients with uncontrolled asthma.