Comparison of pressure controlled and volume controlled ventilation in morbidly obese patients underwent laparoscopic sleeve gastrectomy: A randomized controlled trial

Abstract

Objective: To compare the influence of pressure controlled ventilation (PCV) and the volume controlled ventilation (VCV) on blood gas and respiratory mechanics during the operation in morbidly obese patients who underwent laparoscopic sleeve gastrectomy. Mate-rial and Methods: One hundred patients who had a body mass index above 35 were divided into PCV (Group A) and VCV groups (Group B). Heart rate, mean arterial pressure, SpO2, end-tidal CO2, tidal volume, frequency, Ppeak, Pplateau, compliance values were recorded at baseline, in every 15 minutes after the CO2 insufflation and at 15th minute after the termination of the insufflation for each patient. Arterial blood gas samples were obtained at baseline, in the 15th and 60th minutes after the in-sufflation and at 15th minute after the termination of the insufflation. Results: The mean levels of Ppeak and Pplateau were significantly lower in Group A than Group B in all measurement points. The PCV also increased compliance at 15th min of insufflation and at the end of operation. There was no significant difference between the groups regarding the mean values of pH, PaO2, PCO2, HCO3, BE, PAO2-PaO2. Conclusion: In laparoscopic sleeve gastrectomy, the PCV mode decreased Ppeak and Pplateau levels and increased compliance. The PVC found to have an advantage to VCV during the perioperative period.