The power of the fisher permutation test in 2x k tables

Abstract

The power of the Fisher permutation test extended to 2 x k tables is evaluated unconditionally as a function of the underlying cell probabilities in the table. These results are then applied in assessing the sensitivity of two-generation cancer bioassays in which a fixed number of pups from each litter born in the first generation are selected to continue on test in the second generation. In this case, the two rows of the table correspond to two treatment groups and the k columns correspond to the number of animals responding in a litter. The cell probabilities in this application are based on a suitable beta-binomial superpopulation model. © 1984, Taylor & Francis Group, LLC. All rights reserved.