A simple mathematical model for relapsing-remitting multiple sclerosis (RRMS)

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Abstract

Multiple sclerosis is one of the most common autoimmune-related neurological disorders affecting the central nervous system. One of its main properties is dissemination of lesions in time and space. Here, we propose a simple mathematical model to describe the stages of disease progression with recurrence. We tried to find the steady states and evaluated their stability to identify the necessary conditions to produce the recurrence. Also, we described the analytical results with some numerical simulations.

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Elettreby, M. F., & Ahmed, E. (2020). A simple mathematical model for relapsing-remitting multiple sclerosis (RRMS). Medical Hypotheses, 135. https://doi.org/10.1016/j.mehy.2019.109478

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