RecA kicks Pol V into gear

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Abstract

Although RecA filaments are required for genetic recombination, it now seems that they are not required for translesion synthesis and that they actually inhibit this process. This finding along with elegant biochemical studies of mutant proteins moves us closer to discerning the direct role of RecA protein in SOS mutagenesis.

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Sweasy, J. B. (2005). RecA kicks Pol V into gear. Nature Structural and Molecular Biology. https://doi.org/10.1038/nsmb0305-215

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