Therapeutic drug monitoring and pharmacogenetics to tune imatinib exposure in gastrointestinal stromal tumor patients: hurdles and perspectives for clinical implementation

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Abstract

Present evidence supports the use of intensified pharmacologic monitoring of #imatinib including #TherapeuticDrugMonitoring and #PGx to improve outcomes in patients with GI stromal tumor. Future studies need to address emerging questions to facilitate implementation in clinics.

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Gagno, S., Fratte, C. D., Posocco, B., Buonadonna, A., Fumagalli, A., Guardascione, M., … Cecchin, E. (2023, December 1). Therapeutic drug monitoring and pharmacogenetics to tune imatinib exposure in gastrointestinal stromal tumor patients: hurdles and perspectives for clinical implementation. Pharmacogenomics. Newlands Press Ltd. https://doi.org/10.2217/pgs-2023-0198

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