Observations on the effects of vibration and noise on plasma ACTH and zinc levels, pregnancy and respiration rate in the guineapig

Abstract

The responses of female guineapigs to vibration and noise were examined with the use of an apparatus designed to simulate transport. Peak levels of plasma ACTH and zinc concentrations were attained after 4 min of exposure to vibration and 80-90 dB of noise. The respiration rate, normally around 90/min, was increased to 103/min when the animals were moved (while still in their cages) to the experimental area; it rose to 129/min when the apparatus was switched on to expose the animals to vibration and noise. Those left adjacent to the apparatus and exposed to noise alone elevated their respiration rates to 115/min. Respiration rates returned to normal within 2·5 h. There was no apparent effect on the maintenance of pregnancy, gestation length, litter size or post-partum growth of the young born to guineapigs exposed to this vibration and noise for a period of 1 h at mid-term. © 1986, Royal Society of Medicine Press. All rights reserved.