(Cyanomethylene)tributylphosphorane (CMBP), which promoted the alkylation of various nucleophiles (HA) with alcohols (ROH) to give RA (Mitsunobu-type reaction), was prepared in two steps starting from chloroacetonitrile. © 2005 Pharmaceutical Society of Japan.
CITATION STYLE
Sakamoto, I., Nishii, T., Ozaki, F., Kaku, H., Tanaka, M., & Tsunoda, T. (2005). Preparation of (cyanomethylene)tributylphosphorane: A new mitsunobu-type reagent. Chemical and Pharmaceutical Bulletin, 53(11), 1508–1509. https://doi.org/10.1248/cpb.53.1508
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