Acute liver failure due to trovafloxacin: CT findings

Abstract

Symptomatic drug-induced hepatic adverse events due to trovafloxacin, a new fluoroquinolone antibiotic, are uncommon, but recent severe reactions have led to restriction on its use. We report the clinical course and computed tomography findings in a patient who developed acute liver failure shortly after commencing treatment with trovafloxacin. Extensive hepatic necrosis occurred and the patient ultimately died of her liver disease.