Granulocytic ehrlichiosis in tick-immune guinea pigs.

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Abstract

We investigated whether Ixodes scapularis-mediated host immunity interrupts transmission of the agent of human granulocytic ehrlichiosis (aoHGE) to guinea pigs. Ticks infected with aoHGE readily transmitted aoHGE to tick-immune guinea pigs, despite incomplete tick engorgement and host attachment. Although tick immunity can prevent Lyme borreliosis, protection is not afforded against granulocytic ehrlichiosis.

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Das, S., Deponte, K., Marcantonio, N. L., Ijdo, J. W., Hodzic, E., Katavolos, P., … Fikrig, E. (1998). Granulocytic ehrlichiosis in tick-immune guinea pigs. Infection and Immunity, 66(4), 1803–1805. https://doi.org/10.1128/iai.66.4.1803-1805.1998

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