Human contact with phthalates during early life stages leads to weight gain and obesity

Abstract

When human is exposed to endocrine-disrupting chemicals (EDCs) such as phthalates, for example, di(2-ethylhexyl) phthalate(DEHP) and diisononyl phthalate (DINP)in early life may contribute to overweight and obesity. EDCs are also called obesogen. Obesogen can promote adipogenesis and cause weight gain. Phthalates are man-made chemicals used in polyvinyl (PVC) products such as wires, cables, floorings, wall coverings, medical devices and cosmetics. The vulnerability of humans to EDCs has resulted in adverse health consequences, including decreased sperm motility, infertility in men, coronary heart disease, high blood pressure, atherosclerosis, and obesity. This paper will educate people all over the world about the danger associated with contact with phthalates. It will also help to make people limit exposure to materials made of phthalates.