A convenient synthesis of cross-linked homodimeric bis-lexitropsins

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Abstract

A general synthetic route to cross-linked homodimeric bis-lexitropsins connected through the nitrogens of the central pyrrole ring with polymethylene chains (19a-c, 20a and 21a) is described. These compounds were designed for efficient DNA minor groove binding. © 1995, Taylor & Francis Group, LLC. All rights reserved.

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Al-Said, N. H., & Lown, J. W. (1995). A convenient synthesis of cross-linked homodimeric bis-lexitropsins. Synthetic Communications, 25(7), 1059–1070. https://doi.org/10.1080/00397919508012668

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