Abstract
In 2019, the European Society of Cardiology and European Atherosclerosis Society released a new guideline document with substantial changes regarding the assessment of cardiovascular risk and treatments. The update of high-risk criteria and categories led to a better detection and primary prevention of patients at risk of a first cardiovascular event. Nonetheless, additional efforts are needed for a better inclusion of risk modifiers, especially specific to women, to improve risk stratification and direct primary prevention. Eventually, we discuss how these new guidelines implement PCSK9 inhibitors for very high-risk individuals and the evidence supporting new low-density lipoprotein cholesterol goals below, such as 55 and 40 mg/dL.
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Zeitouni, M., Sabouret, P., Kerneis, M., Silvain, J., Collet, J. P., Bruckert, E., & Montalescot, G. (2021, July 1). 2019 ESC/EAS Guidelines for management of dyslipidaemia: Strengths and limitations. European Heart Journal - Cardiovascular Pharmacotherapy. Oxford University Press. https://doi.org/10.1093/ehjcvp/pvaa077
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