Serum C reactive protein level in type 2 diabetes mellitus patients attending diabetic clinic in Benin City, Nigeria

Abstract

C reactive protein is sensitive physiological biomarkers of sub clinical inflammation associ-ated with hyperglycemia. The aim of this study is to determine the fasting serum C reactive protein level in type 2 diabetes mellitus patients attending diabetic clinic in Benin City, Nigeria. The population sample consists of 142 subjects. 71 patients were known type 2 diabetes mellitus, while the other 71 were age matched control subjects. Fasting glucose and C reactive protein were estimated using glucose oxidase method and ELISA method respectively. The age group that has the highest number of type 2 diabetes mellitus was 41 -50 (64% of males and 36% of the females). Our finding revealed that C reac-tive protein and serum glucose level of type 2 Diabetes mellitus in both females and males show a statistically significant increase as com-pared with age matched Control subjects, (P < 0.05). An elevation of serum C-reactive protein was demonstrated in both males and females type 2 diabetes mellitus in Benin City, Nigeria. These data support a possible role of inflam-matory biomarkers in diabetogenesis.