Experiment research on bonding effect of poly(lactic-co-glycolic acid) device by surface treatment method

Abstract

According to the low temperature and high effective bonding problem of microdevices made of degradable polymer PLGA, chemical, plasma, and UV irradiation method are used to study the experimental surface treatment of PLGA films and microdevices bonding process. The results show that all three methods can reduce the surface contact angle of PLGA films, the contact angle increases with time at room temperature, and the PLGA films contact angle is almost unchanged under refrigeration. The PLGA film bonding temperature is significantly reduced after UV irradiation, and the bonding interfaces also generate diffusion cross linking layer are dense and uniform.