Cytokines: Applications in Domestic Food Animals

Abstract

Cytokines such as human, bovine, and porcine interferons and human and bovine interleukin-1 and interleukin-2 have been used in vivo in cattle and pigs. Colony-stimulating factors and tumor necrosis factor α have been evaluated in vitro in food animals. Studies to evaluate cytokines in domestic food animals have munomodulation is possible in immunosuppressed or pathogen-exposed animals. Cytokine prophylaxis or therapy in food animals may have the greatest potential for control of respiratory disease and mastitis. © 1991, American Dairy Science Association. All rights reserved.