Considerations in selecting postoperative analgesia for pregnant sheep following fetal instrumentation surgery

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Abstract

Implications • As a model of human pregnancy, research studies in catheterized fetal sheep have made significant contributions to our understanding of both normal and abnormal fetal development. • Owing to the invasive nature of catheterization surgery, effective postoperative analgesia is required. • Decisions regarding appropriate analgesia should consider effectiveness in reducing maternal pain and fetal well-being as well as potential impacts upon fetal physiological parameters under investigation. • The reporting of analgesic regimes in all research studies should comply with the ARRIVE guidelines.

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Varcoe, T. J., Darby, J. R. T., Gatford, K. L., Holman, S. L., Cheung, P., Berry, M. J., … Morrison, J. L. (2019). Considerations in selecting postoperative analgesia for pregnant sheep following fetal instrumentation surgery. Animal Frontiers, 9(3), 60–67. https://doi.org/10.1093/af/vfz019

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