The determination of the phases of the structure factors of non-centrosymmetric crystals by the method of double isomorphous replacement

Abstract

It is shown that the complete structure of a non-centrosymmetric crystal can be determined from the X-ray diffraction data obtained from the members of an isomorphous series in which two dif- ferent parts of the structure can be varied independently. The structure so determined may be an enantiomorph of the true structure.