MRI-Guided Focused Ultrasound in Parkinson’s Disease and Essential Tremor: Incisionless but Invasive. A Narrative Review

Abstract

Magnetic resonance-guided focused ultrasound (MRgFUS) is an emerging and promising technology for treating movement dis-orders, such as essential tremors and tremor-dominant Parkinson’s disease. MRgFUS utilizes advanced ultrasound transducer emit-ters to condense sound waves at a precisely defined point. This technology can target various brain areas, such as the pallidothalam-ic tract, thalamus, and pallidum, to ameliorate some of the symptoms of Parkinson’s disease and other movement disorders, such as dystonic and action-induced tremors. We review the current status of preclinical and clinical trials on the clinical use, treatment outcomes, and indications of MRgFUS.