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Complications following postoperative combined radiation and chemotherapy in adenocarcinoma of the rectum and rectosigmoid: A randomized trial that failed

Cancer (1984) 54(11) 2363-2366
DOI: 10.1002/1097-0142(19841201)54:11<2363::AID-CNCR2820541110>3.0.CO;2-U
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Abstract

A randomized multicenter trial was started to evaluate the effect of irradiation combined with 5‐fluorouracil and methotrexate on survival after surgery for rectal and rectosigmoidal carcinoma, Dukes' stages B and C. The trial was terminated prematurely after entrance of 34 patients due to frequent and serious complications. Three patients died as a direct consequence of the adjuvant treatment. Copyright © 1984 American Cancer Society

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APA

Sparsø, B. H., von der Maase, H., Kristensen, D., Christiansen, J., Nielsen, S. Å. D., Hebjørn, M., & Andersen, B. (1984). Complications following postoperative combined radiation and chemotherapy in adenocarcinoma of the rectum and rectosigmoid: A randomized trial that failed. Cancer, 54(11), 2363–2366. https://doi.org/10.1002/1097-0142(19841201)54:11<2363::AID-CNCR2820541110>3.0.CO;2-U

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