The diagnostic performance of serum LIM homeobox transcription factor 1 alpha in patients with gastric cancer

Abstract

The study was conducted to investigate the diagnostic performance of serum LIM homeobox transcription factor 1 alpha (LMX1A) in patients with gastric cancer (GC). The serum level of LMX1A in GC, benign, and healthy groups was measured using quantitative real time PCR (qRT-PCR) and compared with the student t test. The associations of serum LMX1A levels with clinical parameters were analyzed with chi-square test. The diagnostic value of serum LMX1A in GC was evaluated by receiver operating characteristic (ROC) curve. The level of serum LMX1A in GC group (1.309±0.553) was significantly lower than that in the benign group (2.174±0.676) and healthy group (2.598±0.826) (P