Study of Effects of Consumption of Powdered Fenugreek Seeds on Serum Lipid Profile in Patients with Type 2 Diabetes Mellitus

Abstract

Objectives: The aim of our study was to determine the role of fenugreek seed powder on serum lipid profile in patients of type 2 Diabetes Mellitus. Methods: Of all the patients attending the medicine OPD of Muzaffarnagar Medical College & Hospital from June 2012-August 2014, 100 patients of Type II Diabetes Mellitus were selected randomly, including both male and female of age group 40-75 years. They were then divided into 2 groups, study group and control group. One group consisting of fifty patients was given only Anti-Diabetic treatment (control group) and another group consisting of fifty patients was given 50 gm of powdered fenugreek seeds in two divided doses in their diet along with their Anti-Diabetic treatment (study group). All the hundred patients included in the study were on lifestyle modification also. Their serum fasting lipid profile levels were repeated every two months for a study period of six months and then the data from study and control group was evaluated and compared. Results: There was significant reduction in total cholesterol, low density lipoprotein, very low density lipoprotein, and triglyceride and significant rise in the high density lipoprotein levels. Conclusion: The result support the hypothesis and the research question that fenugreek supplement with usual medical care for Type II Diabetes Mellitus is more effective than the usual medical care alone. Therefore, it is recommended that fenugreek supplementation is safe and may be considered in Diabetic patients as a potential means to lower the serum lipid profile level.