A study to review the appropriateness of drug dosage in renally impaired patient by identifying, analysing, and adjusting dosages in a tertiary care teaching hospital

Abstract

Objective: The objective of this study is to identify and analyze drug dosing in renally impaired patient in a tertiary care teaching hospital and to categorize patients on the basis of gender, age, glomerular filtration rate (GFR), and anemia. Methods: A prospective, interventional study was conducted on the drug dosage in renally impaired patient by identifying, analyzing, and adjusting. Ethical clearance was obtained from the Institutional Ethical Committee. The study was conducted on 103 patients with renal impairment for 6 months. During ward rounds, cases were collected, and collected data were assessed and analyzed using Micromedex, Lexicomp. For the possible interventions, the dosage errors were reported along with the evidence. Results: Out of the 103 patients, 73 were males, and 30 were females, and majority of patients belonged to the age group between 41 and 65 years. About 56.31% and 43.69% of patients were in the Category B and Category C of GFR, respectively. A total of 244 comorbidities were present in 103 patients with hypertension and Type 2 diabetes mellitus the foremost. In total, 983 drugs were prescribed to the total patient with an average of 9.54 drugs per patient, 175 drugs required dosage adjustment. Conclusion: The present study effectively reports all the interventions to the physicians along with the supporting data. Continuous medical education to the physicians together with pharmacists may reduce the chances of incongruity in drugs given to the renally impaired patients.