Chemical studies on the constituents of the Chinese medicinal herb Euphorbia helioscopia L.

Abstract

Euphoheliosnoid D (1), a new jatrophone-type diterpenoid, was isolated together with 22 known metabolites from the Chinese medicinal herb Euphorbia helioscopia L. The structure and relative stereochemistry of 1 was elucidated on the basis of spectroscopic methods. Compounds 14-23 were obtained from the species for the first time while compound 14, 2α-hydroxy helioscopinolide B, was isolated as a new natural product. © 2006 Pharmaceutical Society of Japan.