Glycosaminoglycan-mimetic biomaterials. 1. Nonsulfated and sulfated glycopolymers by cyanoxyl-mediated free-radical polymerization

Abstract

A series of N-acetyl-D-glucosamine-containing glycomonomers was synthesized as an initial step in the synthesis of glycosaminoglycanmimetic glycopolymers. It was shown that cyanoxyl-mediated free-radical polymerization is an original and straightforward approach for obtaining water-soluble glycopolymers with high monosaccharide contents and low polydispersity indexes.