Esofagitis eosinofílica

Abstract

Eosinophilic esophagitis is a disease characterized by eosinophilic infiltration of the esophageal mucosa. The symptoms, in the majority of the cases, are indistinguishable from gastroesophageal reflux disease, and include vomiting, regurgitation, nausea, epigastric pain and dysphagia, but the patients rarely respond to antireflux therapy. We report the cases of two girls who presented gastrointestinal symptoms compatible with gastroesophageal reflux disease. They had no notable history of allergic reactions, but responded poorly to antireflux medication. Esophagogastroscopy and esophageal biopsy revealed the presence of eosinophilic esophagitis. The girls were found to be allergic to certain foods and showed a satisfactory improvement when these foods were eliminated from their diets.