Transition to Enteral Triazole Antifungal Therapy for Pediatric Invasive Candidiasis: Secondary Analysis of a Multicenter Cohort Study Conducted by the Pediatric Fungal Network

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Abstract

Of 319 children with invasive candidiasis, 67 (21%) transitioned from intravenous to enteral antifungal therapy. Eight (12%) transitioned back to intravenous antifungal therapy, one due to perceived treatment failure defined by clinical progression or worsening. Global treatment response at study completion was successful in 66 participants who transitioned to enteral therapy.

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Bucayu, R. F. T., Boge, C. L. K., Yildirim, I., Avilés-Robles, M., Vora, S. B., Berman, D. M., … Wattier, R. L. (2024). Transition to Enteral Triazole Antifungal Therapy for Pediatric Invasive Candidiasis: Secondary Analysis of a Multicenter Cohort Study Conducted by the Pediatric Fungal Network. Journal of the Pediatric Infectious Diseases Society, 13(12), 633–638. https://doi.org/10.1093/jpids/piae116

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