Synthesis of new C2 -symmetric six-membered nhcs and their application for the asymmetric diethylzinc addition of arylaldehydes

Abstract

A concise method for the preparation of new 3,4,5,6-tetrahydropyrimidinium salts was presented in this paper. Further application of these salts in asymmetric diethylzinc addition of arylaldehydes was explored, giving the corresponding chiral second alcohols in good yields and moderate enantioselectivities.