Manganese Doping in Biomass Derived Carbon Dots Amplifies White Light-Induced Antibacterial Activity

Abstract

The prevalence of antibiotic-resistant bacterial infections demands effective alternative therapeutics of antibiotics, whereas biocompatible zero-dimensional nanomaterials are an excellent option due to their small size. In this study, we report the one-step hydrothermal approach that was used to synthesize luminescent manganese doped carbon dots (Mn-Cdots) with an efficient quantum yield of 9.2% by employing green Psidium guajava L. (Guava) leaf as the precursor. High-resolution microscopy TEM was used to investigate the average particle size of Mn-Cdots, which was found to be 2.9 ± 0.045 nm. The structural properties and elemental composition of Mn-Cdots were analyzed by FTIR, XRD, EPR, and XPS spectroscopy, and the optical properties of Mn-Cdots were examined by UV-visible and fluorescent spectroscopy. Light-mediated antibacterial activity of Mn-Cdots was investigated by Gram-negative bacteria E. coli under white, blue, and yellow light. The doping effect of a minute quantity of Mn in Mn-Cdots increased the level of ROS generation in the presence of white lights compared to Cdots. Thus, Mn-Cdots might act as potent antibacterial agents.