Mixed Mg/Li amides of the type R2NMgCl·LiCl as highly efficient bases for the regioselective generation of functionalized aryl and heteroaryl magnesium compounds

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Abstract

(Chemical Equation Presented) Two are better than one: Mixed lithium-magnesium complexes of the type R2NMgCl·LiCl are kinetically highly active bases that convert a range of polyfunctional aromatic and heteroaromatic substrates into the corresponding magnesiated derivatives with high regioselectivity. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

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Krasovskiy, A., Krasovskaya, V., & Knochel, P. (2006). Mixed Mg/Li amides of the type R2NMgCl·LiCl as highly efficient bases for the regioselective generation of functionalized aryl and heteroaryl magnesium compounds. Angewandte Chemie - International Edition, 45(18), 2958–2961. https://doi.org/10.1002/anie.200504024

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