Lobular carcinoma may arise within the epithelial component of fibroadenoma of the breast, as evidenced by 5 cases reported from the files of the Mayo Clinic and 21 cases cited in the literature. The 5 cases reported here occurred in a series of 4000 cases of fibroadenoma during a 43‐year period. Lobular carcinoma is the more frequent type to be seen in fibroadenoma (in 22 of 26 cases); it usually develops in situ. Extra‐adenomatous carcinoma of the ipsilateral breast was identified in 11 of 26 cases, and 3 cases of contralateral carcinoma were noted in the entire series. Thus, lobular carcinoma arising within the epithelial component of a fibroadenoma has biological features similar to the behavior of lobular carcinoma of the breast in general. The prognosis has been favorable; lesions are usually encountered early; in only 2 of 26 cases were there axillary metastases. Copyright © 1975 American Cancer Society
CITATION STYLE
Buzanowski‐Konakry, K., Harrison, E. G., & Payne, W. S. (1975). Lobular carcinoma arising in fibroadenoma of the breast. Cancer, 35(2), 450–456. https://doi.org/10.1002/1097-0142(197502)35:2<450::AID-CNCR2820350223>3.0.CO;2-R
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