relationship between risk factor and clinical type of vitiligo in dermatology and venerology outpatient clinic Dr. Soetomo General Academic Hospital Surabaya

Abstract

Vitiligo is a skin and mucosa depigmentation condition caused by the loss of functioning melanocytes. Various pathological mechanisms are involved in melanocytes, their full details are often difficult to explain and several risk factors for vitiligo are thought to play a role. This study describe the relationship between risk factors and clinical type of vitiligo. This study is an analytic observational study with a retrospective cross sectional design based on the medical records patients who were treated in Dermatology and Venerology Outpatient Clinic Dr. Soetomo General Academic Hospital Surabaya. The result of this study found 115 new vitiligo patients with the following characteristics were female (53.9%), late adolescence (26.96%) and students (25.22%). The most common risk factors were idiopathic (51.3%) and emotional (28.7%). The most common clinical type was non-segmental vitiligo (53.04%). There was relationship between emotional and the clinical type of vitiligo (p=0.023 p<0.05) and there was relationship between idiopathic risk factors and the clinical type of vitiligo (p=0.019 p<0.05). There was relationship between emotional risk and idiopathic factors with the clinical type of vitiligo that were related to pathogenesis becomes important to understand to identify therapeutic targets and prognostic implications to stop the progression of the disease.