Teratogenic Genesis in Fetal Malformations

Abstract

Congenital anomalies can occur during the developmental stages of the embryo, from abnormal genetics passed on from the parents or from vivid environmental factors. While advanced technologies are able to detect chromosomal abnormalities, there are many unknown non-genetic variants. Teratogenic factors pose a greater risk to the fetus, as these abnormalities may go undetected until birth. These malformations are the origin of the infant's postnatal illness and disability. The defects can also lead to mortality. The loss can also affect families, as they are affected by not only the loss but also financially. Most of the teratogenic-induced anomalies, once detected, maybe rehabilitated naturally. Those who do require medical intervention pose their own risks, similar to those of infections. Therefore, environmental exposure to teratogens can create long-lasting effects that range from infertility, intrauterine growth restriction, structural defects, and functional central nervous system abnormalities that may lead to fetal death.