Abstract
The gut-brain axis (GBA) connects the gastrointestinal (GI) system and the central nervous system (CNS) in a two-way communication system that greatly impacts mental health and overall well-being. Dietary choices significantly influence the gut microbiome, thereby affecting emotional, cognitive, and neurological health. This review explores how specific dietary patterns, including high-fiber, plant-based, and Mediterranean diets (MD), enhance microbial diversity, decrease inflammation, and enhance gut-brain communication. It highlights the importance of probiotics, prebiotics, omega-3 fatty acids, and antioxidants in controlling gut microbiota, enhancing intestinal barrier function, and reducing systemic inflammation associated with anxiety, depression, and cognitive decline. The article covers practical methods for integrating dietary adjustments into personalized mental health treatment, while also addressing challenges such as individual microbiome variability and the need for long-term research. This review underscores the possibility of using nutritional interventions as a non-invasive and easily accessible way to promote mental health and resilience based on existing evidence. The methodology involved a comprehensive examination of existing literature exploring the GBA and its influence on mental health. We searched relevant databases, including PubMed and Google Scholar, using keywords such as "gut-brain axis," "microbiome," "diet," and "mental health." Peer-reviewed articles were selected based on their relevance to the relationship between dietary interventions and mental health outcomes, with a focus on studies exploring cognitive and emotional well-being.
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CITATION STYLE
Patil, S., & Mehdi, S. S. (2025). The Gut-Brain Axis and Mental Health: How Diet Shapes Our Cognitive and Emotional Well-Being. Cureus. https://doi.org/10.7759/cureus.88420
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