Impact of multiplex polymerase chain reaction testing in patients with bacteremia

Abstract

Rapid identification of the bacteria causing bloodstream infections is essential for timely and effective treatment. Traditional laboratory methods are often time-consuming, thus delaying therapy. Therefore, this study examined the application of the FilmArray blood culture identification panel, a rapid molecular test that can detect multiple pathogens and resistance genes within 1 h. We found that introducing this test during limited hours did not improve patient outcomes; rather, achieving optimal clinical impact may depend on continuous availability and effective collaboration with clinical decision-makers. This study emphasizes the need for unlimited access to rapid testing and support from stewardship programs to optimize clinical outcomes from this diagnostic technology in managing bloodstream infections.