Plasmid-mediated carbapenem-hydrolyzing enzyme KPC-2 in an Enterobacter sp.

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Abstract

A strain of an Enterobacter sp. with reduced susceptibility to imipenem, which produced a plasmid-mediated class A carbapenem-hydrolyzing enzyme, KPC-2 β-lactamase, was isolated from a patient with sepsis at a Boston hospital. This is the first report of the production of a plasmid-encoded KPC-2 β-lactamase by an Enterobacter sp.

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Hossain, A., Ferraro, M. J., Pino, R. M., Dew, R. B., Moland, E. S., Lockhart, T. J., … Hanson, N. D. (2004). Plasmid-mediated carbapenem-hydrolyzing enzyme KPC-2 in an Enterobacter sp. Antimicrobial Agents and Chemotherapy, 48(11), 4438–4440. https://doi.org/10.1128/AAC.48.11.4438-4440.2004

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