Immune-enhancing effects of polysaccharides MLN-1 from by-product of Mai-luo-ning in vivo and in vitro

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Abstract

In this study, a typical Chinese medicine injection (Mai-luo-ning, MLN) was chosen to study the transformation possibility of its by-products (polysaccharides). What’s more, the basic properties of polysaccharides were also detected and its immunoprotect and anti-inflammatory activity were both proved in vivo and in vitro. The experiment determined that MLN-1 significantly increased the level of anti-inflammatory-related factors and the number of lymphocytes. Acute oral toxicity study established that MLN-1 has a non-toxic effect. The present work successfully showed that MLN-1 has the potential to be developed as a food additive.

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Nie, L., Xiao, Q., Liu, S., Li, B., Duan, J., Fan, Y., … Zhu, H. (2019). Immune-enhancing effects of polysaccharides MLN-1 from by-product of Mai-luo-ning in vivo and in vitro. Food and Agricultural Immunology, 30(1), 369–384. https://doi.org/10.1080/09540105.2019.1582612

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