The molecular mechanism of rhein in diabetic nephropathy

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Abstract

Diabetic nephropathy (DN) is characterized by unclear pathogenesis. Recent medical data shows that the incidence of DN rises year by year. Rhein is the main compositions of rhubarb, a traditional Chinese medicinal plant, which plays an active role in kidney protection. The prophylaxis and phytotherapeutic effects of rhein are due to its anti-inflammatory and antifibrosis properties. Here, we shed light on the renal protective role of rhein in diabetes mellitus (DM) with a particular focus on the molecular basis of this effect.

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Zeng, C. C., Liu, X., Chen, G. R., Wu, Q. J., Liu, W. W., Luo, H. Y., & Cheng, J. G. (2014). The molecular mechanism of rhein in diabetic nephropathy. Evidence-Based Complementary and Alternative Medicine. Hindawi Publishing Corporation. https://doi.org/10.1155/2014/487097

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