Diffuse gliomas in an adolescent with multiple enchondromatosis (Ollier's disease)

Abstract

Ollier's disease is characterized by the hamartoma-tous proliferation of cartilage cells, producing masses termed chondromas. A patient presented with Ollier's disease which was found to be associated with diffuse gliomas. Investigating this disease is crucial as there is a high risk of sarcomatous transformation of the skeletal lesions as well as an increased risk of developing extra-osseous malignancies.