Clonal Expansion of Antigen-Specific CD4 T Cells following Infection with Salmonella typhimurium Is Similar in Susceptible ( Ity s ) and Resistant ( Ity r ) BALB/c Mice

Abstract

The results show that CD4 T cells specific for a recombinant antigen expressed in Salmonella typhimurium proliferate normally in mice that express the susceptible form of the Ity gene at early times after infection but do not retain the capacity to produce gamma interferon later in the infection.