Recent Advances in Pyrazoline Derivatives: A Review

Abstract

Pyrazolines and its fused heterocyclic derivatives tested with diverse pharmacological activity constitute an important class of compounds for new drug development. The synthesis of novel pyrazoline derivatives and investigation of their chemical and biological behavior have gained more importance in recent decades. So far, modifications of the pyrazoline ring have proven highly effective with improved potency and lesser toxicity. The present review provides an in depth view of work done so far on pyrazoline and its biological activities covering anticancer, antimycobacterial, antimicrobial, anticonvulsant, antiinflamatory and cardiovascular activities.Copyright © 2015 iGlobal Research and Publishing Foundation.