Early Response to Ketamine for Suicidal Crisis Reduces Suicidal Events at 3 Months

Abstract

symptoms (Montgomery-Asberg Depression Rating Scale) and SI severity (Columbia-Suicide Severity Rating Scale [C-SSRS]) were assessed at baseline and 7 days postinfusion. Suicidal events were collected from clinical records at 3 months. Results: Ketamine significantly reduced depressive symptoms (β = −11; P < .001) and SI severity (β = −2.0; P < .001) at 7 days after controlling for age, sex, and number of infusions. A direct (β = −0.78; P