A case report of malignant pleural mesothelioma with long‐term disease control after chemotherapy

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Abstract

Long duration of responses to chemotherapy in patients with malignant pleural mesothelioma (MPM) is rare. The authoers report a patients with inoperable MPM who achieved complete remission with combination chemotherapy of cyclophosphamide, doxorubicin, and cisplatin. 5‐Fluorouracil and mitomycin C (FM) induced another remission after recurrence of the tumor. Retreatment with FM after chemotherapy had been stopped for 20 months yielded another continuing response. The overall tumor‐control time is more than 4 years. Literature reviews and the authors' results suggest that MPM may be a chemosensitive tumor in some patients. Additional evaluations of CAP, FM, and methotrexate combination regimens in this disease should be considered. Copyright © 1991 American Cancer Society

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APA

Umsawasdi, T., Dhingra, H. M., Charnsangavej, C., & Luna, M. A. (1991). A case report of malignant pleural mesothelioma with long‐term disease control after chemotherapy. Cancer, 67(1), 48–54. https://doi.org/10.1002/1097-0142(19910101)67:1<48::AID-CNCR2820670110>3.0.CO;2-I

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