Novel composite materials for chiral separation from cellulose and barium sulfate

Abstract

Cellulose was dissolved in an aqueous solution of sodium hydroxide (NaOH) and urea followed by the addition of barium sulfate (BaSO to yield the BaSOcellulose composite particles. The morphology, particle size, and BaSOcontent of the composite particles were adjusted by controlling the feed ratio of cellulose and BaSO The cellulose within the composite particles then reacted with 3,5-dimethylphenyl isocyanate. The resulting materials were utilized as the chiral stationary phases (CSPs) whose enantioseparation capabilities were evaluated by various chiral analytes. Due to the mechanical enhancement effect of BaSO the composite particles could be applied to the chromatographic packing materials. © 2013 Wei Chen et al.