Erratum: Effect of probiotic treatment on the clinical course, intestinal microbiome, and toxigenic Clostridium perfringens in dogs with acute hemorrhagic diarrhea (PLoS ONE (2018) 13:9 (e0204691) DOI: 10.1371/journal.pone.0204691)

Abstract

Following publication of this article [1], the authors provide revised text to clarify the composition of the probiotic mixture, sold under the brand Vivomixx in Continental Europe, which was used in the study. The correct fourth sentence of the Treatment subsection of the Materials and Methods is as follows: According to the manufacturer, the probiotic mixture contained the following live bacterial strains: Lactobacillus plantarum, Streptococcus thermophilus, Bifidobacterium breve, Lactobacillus paracasei, Lactobacillus delbrueckii subsp. bulgaricus, Lactobacillus acidophilus, Bifidobacterium longum, and Bifidobacterium infantis; the authors' research did not extend to confirm the bacterial composition information provided by the manufacturer. The authors also provide the following additional information regarding the rationale for the time points used in the study: Day 0 served as a baseline to capture the microbial status before starting the treatment. Day 7 was chosen because previous clinic experience showed that most dogs with acute hemorrhagic diarrhea syndrome (AHDS) recover clinically within this time period. Day 21 was chosen since the probiotic or placebo was administered until this day.